Home News Path of Exile 2: The Slithering Dead Quest Guide

Path of Exile 2: The Slithering Dead Quest Guide

by Sadie Feb 21,2025

This guide details the Path of Exile 2 side quest, "The Slithering Dead," including a step-by-step walkthrough and a comprehensive analysis of the reward choices.

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The Slithering Dead quest, initiated by Servi in the Ziggurat Encampment, tasks players with uncovering the fate of her son and the secrets of a rival tribe. While the quest itself is straightforward, selecting the appropriate reward presents a challenge. Players have a single, irreversible choice among three options.

The Slithering Dead Quest Walkthrough (Step-by-Step)

To begin, locate the Venom Crypts entrance within the Jungle Ruins map (Act 3 and Act 3 Cruel). It's situated near the Waypoint. The Venom Crypts are optional; you can revisit them later if missed.

Explore the Venom Crypts until you discover a corpse in the Den of the Serpent Priestess (location varies due to map randomization).

Interact with the corpse to obtain Corpse-Snake Venom. Return to Servi in the Ziggurat Encampment to complete the quest.

Choosing Your Venom Draught Reward in The Slithering Dead

The Slithering Dead is repeatable (Act 3 and Act 3 Cruel), offering different rewards each time.

Act 3 Reward Choices

Servi presents three Venom Draughts:

Venom Draught Effect
Venom Draught of Stone 25% increased Stun Threshold
Venom Draught of the Veil 30% increased Elemental Ailment Threshold
Venom Draught of Clarity 25% increased Mana Regeneration Rate

The choice is permanent. Venom Draught of Clarity (mana regeneration) is generally the safest and most versatile option, particularly beneficial for melee builds. Venom Draught of the Veil (elemental ailment threshold) is a strong alternative for builds less reliant on mana. Venom Draught of Stone (stun threshold) is the least desirable unless specifically needed to mitigate stun effects.

Act 3 Cruel (Act 6) Reward Choices

The Act 3 Cruel iteration offers:

Venom Draught Effect
Venom Draught of the Lost +10% to Chaos Resistance
Venom Draught of the Sky +5 to All Attributes
Venom Draught of the Marshes 15% Reduced Slowing Potency of Debuffs

Venom Draught of the Lost (+10% Chaos Resistance) is typically the superior choice due to the rarity of Chaos Resistance on gear. Only builds utilizing Chaos Inoculation, often paired with Eternal Youth, might prefer Venom Draught of the Sky (+5 to all attributes) for its attribute boost.

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